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Proximal GATA-binding sites are essential for human HSD3B1 gene transcription in the placenta

The enzyme 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD) is involved in the synthesis of active steroid hormones. Two human 3β-HSD isoforms are expressed in a tissue-specific pattern. HSD3B1 (type I) expression is essential to produce progesterone for pregnancy maintenance. To understand the me...

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Detalles Bibliográficos
Autores principales:	Lai, Tsai-Chun, Li, Hsiao-Fang, Li, Yu-Shian, Hung, Pei-Yu, Shyu, Ming-Kwang, Hu, Meng-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487343/ https://www.ncbi.nlm.nih.gov/pubmed/28655875 http://dx.doi.org/10.1038/s41598-017-04133-6

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