IGF1R deficiency attenuates acute inflammatory response in a bleomycin-induced lung injury mouse model

IGF1R (Insulin-like Growth Factor 1 Receptor) is a tyrosine kinase with pleiotropic cellular functions. IGF activity maintains human lung homeostasis and is implicated in pulmonary diseases such as cancer, ARDS, COPD, asthma and fibrosis. Here we report that lung transcriptome analysis in mice with...

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Detalles Bibliográficos
Autores principales: Piñeiro-Hermida, Sergio, López, Icíar P., Alfaro-Arnedo, Elvira, Torrens, Raquel, Iñiguez, María, Alvarez-Erviti, Lydia, Ruíz-Martínez, Carlos, Pichel, José G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487362/
https://www.ncbi.nlm.nih.gov/pubmed/28655914
http://dx.doi.org/10.1038/s41598-017-04561-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487362/
https://www.ncbi.nlm.nih.gov/pubmed/28655914
http://dx.doi.org/10.1038/s41598-017-04561-4

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