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Amyloid-β Impairs Vesicular Secretion in Neuronal and Astrocyte Peptidergic Transmission

Regulated secretion of neuropeptides and neurotrophic factors critically modulates function and plasticity of synapses and circuitries. It is believed that rising amyloid-β (Aβ) concentrations, synaptic dysfunction and network disorganization underlie early phases of Alzheimer’s disease (AD). Here,...

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Detalles Bibliográficos
Autores principales: Plá, Virginia, Barranco, Neus, Pozas, Esther, Aguado, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487408/
https://www.ncbi.nlm.nih.gov/pubmed/28701919
http://dx.doi.org/10.3389/fnmol.2017.00202