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Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities

Chemokines function via G-protein coupled receptors in a robust network to recruit immune cells to sites of inflammation. Due to the complexity of this network, targeting single chemokines or receptors has not been successful in inflammatory disease. Dog tick saliva contains polyvalent CC-chemokine...

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Detalles Bibliográficos
Autores principales: Singh, Kamayani, Davies, Graham, Alenazi, Yara, Eaton, James R. O., Kawamura, Akane, Bhattacharya, Shoumo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487423/
https://www.ncbi.nlm.nih.gov/pubmed/28655871
http://dx.doi.org/10.1038/s41598-017-04378-1