dsRNA Binding Domain of PKR Is Proteolytically Released by Enterovirus A71 to Facilitate Viral Replication

Enterovirus 71 (EV-A71) causes hand, foot and mouth disease in young children and infants, but can also cause severe neurological complications or even death. The double-stranded RNA (dsRNA)-dependent protein kinase R (PKR), an interferon-induced antiviral protein, phosphorylates the regulatory α-su...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Hsiu, Lau, Kean Seng, Kuo, Rei-Lin, Horng, Jim-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487429/
https://www.ncbi.nlm.nih.gov/pubmed/28702377
http://dx.doi.org/10.3389/fcimb.2017.00284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487429/
https://www.ncbi.nlm.nih.gov/pubmed/28702377
http://dx.doi.org/10.3389/fcimb.2017.00284

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