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Administration of a Histone Deacetylase Inhibitor into the Basolateral Amygdala Enhances Memory Consolidation, Delays Extinction, and Increases Hippocampal BDNF Levels

Gene expression related to the formation and modification of memories is regulated epigenetically by chromatin remodeling through histone acetylation. Memory formation and extinction can be enhanced by treatment with inhibitors of histone deacetylases (HDACs). The basolateral amygdala (BLA) is a bra...

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Detalles Bibliográficos
Autores principales: Valiati, Fernanda E., Vasconcelos, Mailton, Lichtenfels, Martina, Petry, Fernanda S., de Almeida, Rosa M. M., Schwartsmann, Gilberto, Schröder, Nadja, de Farias, Caroline B., Roesler, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487430/
https://www.ncbi.nlm.nih.gov/pubmed/28701956
http://dx.doi.org/10.3389/fphar.2017.00415