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A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects

Rationale: Renewed interest has been seen in the use of lysergic acid diethylamide (LSD) in psychiatric research and practice. The repeated use of LSD leads to tolerance that is believed to result from serotonin (5-HT) 5-HT(2A) receptor downregulation. In rats, daily LSD administration for 4 days de...

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Detalles Bibliográficos
Autores principales: Dolder, Patrick C., Grünblatt, Edna, Müller, Felix, Borgwardt, Stefan J., Liechti, Matthias E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487530/
https://www.ncbi.nlm.nih.gov/pubmed/28701958
http://dx.doi.org/10.3389/fphar.2017.00423