Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics

H9N2 avian influenza viruses are enzootic in poultry across Asia and North Africa, where they pose a threat to human health as both zoonotic agents and potential pandemic candidates. Poultry vaccination against H9N2 viruses has been employed in many regions; however, vaccine effectiveness is frequen...

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Detalles Bibliográficos
Autores principales: Peacock, Thomas P., Benton, Donald J., James, Joe, Sadeyen, Jean-Remy, Chang, Pengxiang, Sealy, Joshua E., Bryant, Juliet E., Martin, Stephen R., Shelton, Holly, Barclay, Wendy S., Iqbal, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487547/
https://www.ncbi.nlm.nih.gov/pubmed/28468875
http://dx.doi.org/10.1128/JVI.00218-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487547/
https://www.ncbi.nlm.nih.gov/pubmed/28468875
http://dx.doi.org/10.1128/JVI.00218-17

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