Cargando…

Central Nervous System Infection with Borna Disease Virus Causes Kynurenine Pathway Dysregulation and Neurotoxic Quinolinic Acid Production

Central nervous system infection of neonatal and adult rats with Borna disease virus (BDV) results in neuronal destruction and behavioral abnormalities with differential immune-mediated involvement. Neuroactive metabolites generated from the kynurenine pathway of tryptophan degradation have been imp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Formisano, Simone, Hornig, Mady, Yaddanapudi, Kavitha, Vasishtha, Mansi, Parsons, Loren H., Briese, Thomas, Lipkin, W. Ian, Williams, Brent L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Cellular Response to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487560/ https://www.ncbi.nlm.nih.gov/pubmed/28446679 http://dx.doi.org/10.1128/JVI.00673-17

Ejemplares similares

Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease
por: Honkavuori, Kirsi S., et al.
Publicado: (2008)

Toll-like Receptor 3 Regulates Neural Stem Cell Proliferation by Modulating the Sonic Hedgehog Pathway
por: Yaddanapudi, Kavitha, et al.
Publicado: (2011)

Borna disease.
por: Hatalski, C G, et al.
Publicado: (1997)

Induction of Toll-Like Receptor 3-Mediated Immunity during Gestation Inhibits Cortical Neurogenesis and Causes Behavioral Disturbances
por: De Miranda, Joari, et al.
Publicado: (2010)

Gastric Cancer Cell-Derived Kynurenines Hyperactive Regulatory T Cells to Promote Chemoresistance via the IL-10/STAT3/BCL2 Signaling Pathway
por: Wu, Dandan, et al.
Publicado: (2022)

Application of Novel PCR-Based Methods for Detection, Quantitation, and Phylogenetic Characterization of Sutterella Species in Intestinal Biopsy Samples from Children with Autism and Gastrointestinal Disturbances
por: Williams, Brent L., et al.
Publicado: (2012)

Changing the Face of Kynurenines and Neurotoxicity: Therapeutic Considerations
por: Bohár, Zsuzsanna, et al.
Publicado: (2015)

Dynamics of Virus-Specific Memory B Cells and Plasmablasts following Viral Infection of the Central Nervous System
por: Atkinson, Jeffrey R., et al.
Publicado: (2019)

CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammation
por: Yan, Jingya, et al.
Publicado: (2023)

Characterization of the Kynurenine Pathway and Quinolinic Acid Production in Macaque Macrophages
por: Lim, Chai K., et al.
Publicado: (2013)

Defective Influenza A Virus RNA Products Mediate MAVS-Dependent Upregulation of Human Leukocyte Antigen Class I Proteins
por: Rahim, Mir Munir A., et al.
Publicado: (2020)

Nonparametric methods for the analysis of single-color pathogen microarrays
por: Jabado, Omar J, et al.
Publicado: (2010)

Borna disease virus-specific T cells protect against or cause immunopathological Borna disease
Publicado: (1994)

Borna Disease Virus and the Brain
por: Gonzalez–Dunia, Daniel, et al.
Publicado: (1997)

Bocavirus Episome in Infected Human Tissue Contains Non-Identical Termini
por: Kapoor, Amit, et al.
Publicado: (2011)

Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder
por: Birner, Armin, et al.
Publicado: (2017)

Kynurenines in the Pathogenesis of Peripheral Neuropathy During Leprosy and COVID-19
por: de Oliveira, Jéssica Araujo da Paixão, et al.
Publicado: (2022)

Alpha/Beta Interferon Receptor Signaling Amplifies Early Proinflammatory Cytokine Production in the Lung during Respiratory Syncytial Virus Infection
por: Goritzka, Michelle, et al.
Publicado: (2014)

Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export
por: Killip, Marian J., et al.
Publicado: (2014)

Latency-Associated Viral Interleukin-10 (IL-10) Encoded by Human Cytomegalovirus Modulates Cellular IL-10 and CCL8 Secretion during Latent Infection through Changes in the Cellular MicroRNA hsa-miR-92a
por: Poole, Emma, et al.
Publicado: (2014)

Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity
por: Li, Lian-Feng, et al.
Publicado: (2016)

MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11
por: Ashraf, Usama, et al.
Publicado: (2016)

Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response
por: Conn, Kristen L., et al.
Publicado: (2016)

Venezuelan Equine Encephalitis Virus Induces Apoptosis through the Unfolded Protein Response Activation of EGR1
por: Baer, Alan, et al.
Publicado: (2016)

Analysis of the Early Immune Response to Infection by Infectious Bursal Disease Virus in Chickens Differing in Their Resistance to the Disease
por: Smith, Jacqueline, et al.
Publicado: (2014)

Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage
por: Humoud, Majid N., et al.
Publicado: (2016)

Notwithstanding Circumstantial Alibis, Cytotoxic T Cells Can Be Major Killers of HIV-1-Infected Cells
por: Gadhamsetty, Saikrishna, et al.
Publicado: (2016)

The PB2 Subunit of the Influenza A Virus RNA Polymerase Is Imported into the Mitochondrial Matrix
por: Long, Joshua C. D., et al.
Publicado: (2016)

Protective Capacity of the Human Anamnestic Antibody Response during Acute Dengue Virus Infection
por: Xu, Meihui, et al.
Publicado: (2016)

Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India
por: Chandele, Anmol, et al.
Publicado: (2016)

Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity
por: Zenner, Helen L., et al.
Publicado: (2013)

Influenza A Virus Infection in Pigs Attracts Multifunctional and Cross-Reactive T Cells to the Lung
por: Talker, Stephanie C., et al.
Publicado: (2016)

Differential Immunodominance Hierarchy of CD8(+) T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection
por: Adland, Emily, et al.
Publicado: (2018)

Asian Elephant T Cell Responses to Elephant Endotheliotropic Herpesvirus
por: Fuery, Angela, et al.
Publicado: (2018)

Alpha/Beta Interferon (IFN-α/β) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-γ-Dependent Responses
por: Hwang, Mihyun, et al.
Publicado: (2018)

H5N1 Influenza A Virus PB1-F2 Relieves HAX-1-Mediated Restriction of Avian Virus Polymerase PA in Human Lung Cells
por: Mazel-Sanchez, B., et al.
Publicado: (2018)

Dose of Retroviral Infection Determines Induction of Antiviral NK Cell Responses
por: Littwitz-Salomon, Elisabeth, et al.
Publicado: (2017)

Viperin Targets Flavivirus Virulence by Inducing Assembly of Noninfectious Capsid Particles
por: Vonderstein, Kirstin, et al.
Publicado: (2017)

Tumor Necrosis Factor-Mediated Survival of CD169(+) Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection
por: Shinde, Prashant V., et al.
Publicado: (2018)

The Human CD4(+) T Cell Response against Mumps Virus Targets a Broadly Recognized Nucleoprotein Epitope
por: de Wit, Jelle, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_atm195khklqlui5dcsnfrald3h