Identification of Antifungal H(+)-ATPase Inhibitors with Effect on Plasma Membrane Potential

The plasma membrane H(+)-ATPase (Pma1) is an essential fungal protein and a proposed target for new antifungal medications. The compounds in a small-molecule library containing ∼191,000 commercially available compounds were screened for their ability to inhibit Saccharomyces cerevisiae plasma membra...

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Detalles Bibliográficos
Autores principales: Kjellerup, Lasse, Gordon, Sandra, Cohrt, Karen O'Hanlon, Brown, William Dalby, Fuglsang, Anja Thoe, Winther, Anne-Marie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487681/
https://www.ncbi.nlm.nih.gov/pubmed/28438931
http://dx.doi.org/10.1128/AAC.00032-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487681/
https://www.ncbi.nlm.nih.gov/pubmed/28438931
http://dx.doi.org/10.1128/AAC.00032-17

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