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Identification of Antifungal H(+)-ATPase Inhibitors with Effect on Plasma Membrane Potential
The plasma membrane H(+)-ATPase (Pma1) is an essential fungal protein and a proposed target for new antifungal medications. The compounds in a small-molecule library containing ∼191,000 commercially available compounds were screened for their ability to inhibit Saccharomyces cerevisiae plasma membra...
Autores principales: | Kjellerup, Lasse, Gordon, Sandra, Cohrt, Karen O'Hanlon, Brown, William Dalby, Fuglsang, Anja Thoe, Winther, Anne-Marie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487681/ https://www.ncbi.nlm.nih.gov/pubmed/28438931 http://dx.doi.org/10.1128/AAC.00032-17 |
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