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Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy
The advent of cell reprogramming has enabled the generation of induced pluripotent stem cells (iPSCs) from patient skin fibroblasts or blood cells and their subsequent differentiation into tissue-specific cells, including neurons and glia. This approach can be used to recapitulate disease-specific p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487699/ https://www.ncbi.nlm.nih.gov/pubmed/28593578 http://dx.doi.org/10.1007/s00109-017-1533-5 |