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Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy

The advent of cell reprogramming has enabled the generation of induced pluripotent stem cells (iPSCs) from patient skin fibroblasts or blood cells and their subsequent differentiation into tissue-specific cells, including neurons and glia. This approach can be used to recapitulate disease-specific p...

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Detalles Bibliográficos
Autores principales: Jungverdorben, Johannes, Till, Andreas, Brüstle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487699/
https://www.ncbi.nlm.nih.gov/pubmed/28593578
http://dx.doi.org/10.1007/s00109-017-1533-5