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Cocaine Administration and Its Withdrawal Enhance the Expression of Genes Encoding Histone-Modifying Enzymes and Histone Acetylation in the Rat Prefrontal Cortex

Chronic exposure to cocaine, craving, and relapse are attributed to long-lasting changes in gene expression arising through epigenetic and transcriptional mechanisms. Although several brain regions are involved in these processes, the prefrontal cortex seems to play a crucial role not only in motiva...

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Detalles Bibliográficos
Autores principales: Sadakierska-Chudy, Anna, Frankowska, Małgorzata, Jastrzębska, Joanna, Wydra, Karolina, Miszkiel, Joanna, Sanak, Marek, Filip, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487868/
https://www.ncbi.nlm.nih.gov/pubmed/28393332
http://dx.doi.org/10.1007/s12640-017-9728-7