S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion

DNA replication stress, an important source of genomic instability, arises upon different types of DNA replication perturbations, including those that stall replication fork progression. Inhibitors of the cellular pool of deoxynucleotide triphosphates (dNTPs) slow down DNA synthesis throughout the g...

Descripción completa

Detalles Bibliográficos
Autores principales: Giannattasio, Michele, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487892/
https://www.ncbi.nlm.nih.gov/pubmed/28220209
http://dx.doi.org/10.1007/s00018-017-2474-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487892/
https://www.ncbi.nlm.nih.gov/pubmed/28220209
http://dx.doi.org/10.1007/s00018-017-2474-4

Ejemplares similares