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Skeletal muscle secretome in Duchenne muscular dystrophy: a pivotal anti-inflammatory role of adiponectin

BACKGROUND: Persistent inflammation exacerbates the progression of Duchenne muscular dystrophy (DMD). The hormone, adiponectin (ApN), which is decreased in the metabolic syndrome, exhibits anti-inflammatory properties on skeletal muscle and alleviates the dystrophic phenotype of mdx mice. Here, we i...

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Detalles Bibliográficos
Autores principales: Lecompte, S., Abou-Samra, M., Boursereau, R., Noel, L., Brichard, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487898/
https://www.ncbi.nlm.nih.gov/pubmed/28188344
http://dx.doi.org/10.1007/s00018-017-2465-5