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Advanced glycation end products regulate anabolic and catabolic activities via NLRP3‐inflammasome activation in human nucleus pulposus cells

Intervertebral disc degeneration is widely recognized as a cause of lower back pain, neurological dysfunction and other musculoskeletal disorders. The major inflammatory cytokine IL‐1β is associated with intervertebral disc degeneration; however, the molecular mechanisms that drive IL‐1β production...

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Detalles Bibliográficos
Autores principales: Song, Yu, Wang, Yan, Zhang, Yukun, Geng, Wen, Liu, Wei, Gao, Yong, Li, Shuai, Wang, Kun, Wu, Xinghuo, Kang, Liang, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487914/
https://www.ncbi.nlm.nih.gov/pubmed/28224704
http://dx.doi.org/10.1111/jcmm.13067