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HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation

The upregulation of heme oxygenase-1 (HO-1) is one of the most important mechanisms of cell adaptation to stress. Indeed, the redox sensitive transcription factor Nrf2 is the pivotal regulator of HO-1 induction. Through the antioxidant, antiapoptotic, and antinflammatory properties of its metabolic...

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Detalles Bibliográficos
Autores principales: Nitti, Mariapaola, Piras, Sabrina, Marinari, Umberto M., Moretta, Lorenzo, Pronzato, Maria A., Furfaro, Anna Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488009/
https://www.ncbi.nlm.nih.gov/pubmed/28475131
http://dx.doi.org/10.3390/antiox6020029