NOX2-Induced Activation of Arginase and Diabetes-Induced Retinal Endothelial Cell Senescence

Increases in reactive oxygen species (ROS) and decreases in nitric oxide (NO) have been linked to vascular dysfunction during diabetic retinopathy (DR). Diabetes can reduce NO by increasing ROS and by increasing activity of arginase, which competes with nitric oxide synthase (NOS) for their commons...

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Detalles Bibliográficos
Autores principales: Rojas, Modesto, Lemtalsi, Tahira, Toque, Haroldo A., Xu, Zhimin, Fulton, David, Caldwell, Robert William, Caldwell, Ruth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488023/
https://www.ncbi.nlm.nih.gov/pubmed/28617308
http://dx.doi.org/10.3390/antiox6020043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488023/
https://www.ncbi.nlm.nih.gov/pubmed/28617308
http://dx.doi.org/10.3390/antiox6020043

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