A Pharmacometric Framework for Axitinib Exposure, Efficacy, and Safety in Metastatic Renal Cell Carcinoma Patients

The relationships between exposure, biomarkers (vascular endothelial growth factor (VEGF), soluble VEGF receptors (sVEGFR)‐1, ‐2, ‐3, and soluble stem cell factor receptor (sKIT)), tumor sum of longest diameters (SLD), diastolic blood pressure (dBP), and overall survival (OS) were investigated in a...

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Detalles Bibliográficos
Autores principales: Schindler, E, Amantea, MA, Karlsson, MO, Friberg, LE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488123/
https://www.ncbi.nlm.nih.gov/pubmed/28378918
http://dx.doi.org/10.1002/psp4.12193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488123/
https://www.ncbi.nlm.nih.gov/pubmed/28378918
http://dx.doi.org/10.1002/psp4.12193

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