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A Prospective Population Pharmacokinetic Study on Morphine Metabolism in Cancer Patients

BACKGROUND: Oral and subcutaneous morphine is widely used for the treatment of cancer-related pain; however, solid pharmacokinetic data on this practice are lacking. Furthermore, it is largely unknown which factors contribute to the variability in clearances of morphine and its metabolites and wheth...

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Detalles Bibliográficos
Autores principales: Oosten, Astrid W., Abrantes, João A., Jönsson, Siv, Matic, Maja, van Schaik, Ron H. N., de Bruijn, Peter, van der Rijt, Carin C. D., Mathijssen, Ron H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488155/
https://www.ncbi.nlm.nih.gov/pubmed/27815868
http://dx.doi.org/10.1007/s40262-016-0471-7