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A Prospective Population Pharmacokinetic Study on Morphine Metabolism in Cancer Patients
BACKGROUND: Oral and subcutaneous morphine is widely used for the treatment of cancer-related pain; however, solid pharmacokinetic data on this practice are lacking. Furthermore, it is largely unknown which factors contribute to the variability in clearances of morphine and its metabolites and wheth...
Autores principales: | Oosten, Astrid W., Abrantes, João A., Jönsson, Siv, Matic, Maja, van Schaik, Ron H. N., de Bruijn, Peter, van der Rijt, Carin C. D., Mathijssen, Ron H. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488155/ https://www.ncbi.nlm.nih.gov/pubmed/27815868 http://dx.doi.org/10.1007/s40262-016-0471-7 |
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