Chromatin Regulates Genome Targeting with Cisplatin

Cisplatin derivatives can form various types of DNA lesions (DNA‐Pt) and trigger pleiotropic DNA damage responses. Here, we report a strategy to visualize DNA‐Pt with high resolution, taking advantage of a novel azide‐containing derivative of cisplatin we named APPA, a cellular pre‐extraction protoc...

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Detalles Bibliográficos
Autores principales: Zacharioudakis, Emmanouil, Agarwal, Poonam, Bartoli, Alexandra, Abell, Nathan, Kunalingam, Lavaniya, Bergoglio, Valérie, Xhemalce, Blerta, Miller, Kyle M., Rodriguez, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488169/
https://www.ncbi.nlm.nih.gov/pubmed/28474855
http://dx.doi.org/10.1002/anie.201701144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488169/
https://www.ncbi.nlm.nih.gov/pubmed/28474855
http://dx.doi.org/10.1002/anie.201701144

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