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Biocatalytic Friedel–Crafts Acylation and Fries Reaction

The Friedel–Crafts acylation is commonly used for the synthesis of aryl ketones, and a biocatalytic version, which may benefit from the chemo‐ and regioselectivity of enzymes, has not yet been introduced. Described here is a bacterial acyltransferase which can catalyze Friedel–Crafts C‐acylation of...

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Detalles Bibliográficos
Autores principales: Schmidt, Nina G., Pavkov‐Keller, Tea, Richter, Nina, Wiltschi, Birgit, Gruber, Karl, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488191/
https://www.ncbi.nlm.nih.gov/pubmed/28544673
http://dx.doi.org/10.1002/anie.201703270