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Exploring the Catalytic Promiscuity of Phenolic Acid Decarboxylases: Asymmetric, 1,6‐Conjugate Addition of Nucleophiles Across 4‐Hydroxystyrene

The catalytic promiscuity of a ferulic acid decarboxylase from Enterobacter sp. (FDC_Es) and phenolic acid decarboxylases (PADs) for the asymmetric conjugate addition of water across the C=C bond of hydroxystyrenes was extended to the N‐, C‐ and S‐nucleophiles methoxyamine, cyanide and propanethiol...

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Detalles Bibliográficos
Autores principales: Payer, Stefan E., Sheng, Xiang, Pollak, Hannah, Wuensch, Christiane, Steinkellner, Georg, Himo, Fahmi, Glueck, Silvia M., Faber, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488193/
https://www.ncbi.nlm.nih.gov/pubmed/28713228
http://dx.doi.org/10.1002/adsc.201700247