Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours

Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, is troublesome, which is particularly detrimental in oncology where rearrangements play diag...

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Detalles Bibliográficos
Autores principales: Harewood, Louise, Kishore, Kamal, Eldridge, Matthew D., Wingett, Steven, Pearson, Danita, Schoenfelder, Stefan, Collins, V. Peter, Fraser, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488307/
https://www.ncbi.nlm.nih.gov/pubmed/28655341
http://dx.doi.org/10.1186/s13059-017-1253-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488307/
https://www.ncbi.nlm.nih.gov/pubmed/28655341
http://dx.doi.org/10.1186/s13059-017-1253-8

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