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Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours
Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, is troublesome, which is particularly detrimental in oncology where rearrangements play diag...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488307/ https://www.ncbi.nlm.nih.gov/pubmed/28655341 http://dx.doi.org/10.1186/s13059-017-1253-8 |