Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection

Vectors based on the adeno-associated virus (AAV) are currently the preferred tools for delivering genes to photoreceptors (PR) in small and large animals. AAVs have been applied successfully in various models of PR dystrophies. However, unknown barriers still limit AAV's efficient application...

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Detalles Bibliográficos
Autores principales: Petit, Lolita, Ma, Shan, Cheng, Shun-Yun, Gao, Guangping, Punzo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488363/
https://www.ncbi.nlm.nih.gov/pubmed/28510482
http://dx.doi.org/10.1089/hum.2017.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488363/
https://www.ncbi.nlm.nih.gov/pubmed/28510482
http://dx.doi.org/10.1089/hum.2017.020

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