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Rod Outer Segment Development Influences AAV-Mediated Photoreceptor Transduction After Subretinal Injection
Vectors based on the adeno-associated virus (AAV) are currently the preferred tools for delivering genes to photoreceptors (PR) in small and large animals. AAVs have been applied successfully in various models of PR dystrophies. However, unknown barriers still limit AAV's efficient application...
Autores principales: | Petit, Lolita, Ma, Shan, Cheng, Shun-Yun, Gao, Guangping, Punzo, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488363/ https://www.ncbi.nlm.nih.gov/pubmed/28510482 http://dx.doi.org/10.1089/hum.2017.020 |
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