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Artesunate ameliorates lung fibrosis via inhibiting the Notch signaling pathway

The present study aimed to determine the underlying molecular mechanism of the antifibrotic effect of artesunate in pulmonary fibrosis (PF). Primary lung fibroblasts were isolated from the lung tissues of rats, and treated with artesunate (8 µg/ml) and transforming growth factor (TGF)-β1 (5 ng/ml)....

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Detalles Bibliográficos
Autores principales: Liu, Yujuan, Huang, Guojin, Mo, Biwen, Wang, Changming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488411/
https://www.ncbi.nlm.nih.gov/pubmed/28672967
http://dx.doi.org/10.3892/etm.2017.4573