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Prevention of dendritic and synaptic deficits and cognitive impairment with a neurotrophic compound
BACKGROUND: The use of neurotrophic factors to treat Alzheimer’s disease (AD) is hindered by their blood–brain barrier impermeability, short half-life, and severe side effects. Peptide 021 (P021) is a neurotrophic/neurogenic tetra-peptide that was derived from the most active region of the ciliary n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488423/ https://www.ncbi.nlm.nih.gov/pubmed/28655344 http://dx.doi.org/10.1186/s13195-017-0273-7 |