Conditional knock-out of lipoic acid protein ligase 1 reveals redundancy pathway for lipoic acid metabolism in Plasmodium berghei malaria parasite

BACKGROUND: Lipoic acid is a cofactor for α-keto acid dehydrogenase system that is involved in the central energy metabolism. In the apicomplexan parasite, Plasmodium, lipoic acid protein ligase 1 (LplA1) and LplA2 catalyse the ligation of acquired lipoic acid to the dehydrogenase complexes in the m...

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Detalles Bibliográficos
Autores principales: Wang, Min, Wang, Qiong, Gao, Xiang, Su, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488443/
https://www.ncbi.nlm.nih.gov/pubmed/28655332
http://dx.doi.org/10.1186/s13071-017-2253-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488443/
https://www.ncbi.nlm.nih.gov/pubmed/28655332
http://dx.doi.org/10.1186/s13071-017-2253-y

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