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Downregulation of P16 promotes cigarette smoke extract-induced vascular smooth muscle cell proliferation via preventing G1/S phase transition

The proliferation of vascular smooth muscle cells (VSMCs) serves an important role in cigarette smoking-associated vascular diseases; however, the underlying mechanisms responsible for this remain unclear. The aim of the present study was to elucidate the role of P16 in cigarette smoke extract (CSE)...

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Detalles Bibliográficos
Autores principales: Guo, Tao, Chai, Xiangping, Liu, Qiming, Peng, Wen, Peng, Zhenyu, Cai, Yuzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488496/
https://www.ncbi.nlm.nih.gov/pubmed/28672917
http://dx.doi.org/10.3892/etm.2017.4468