Click-PEGylation – A mobility shift approach to assess the redox state of cysteines in candidate proteins

The redox state of cysteine thiols is critical for protein function. Whereas cysteines play an important role in the maintenance of protein structure through the formation of internal disulfides, their nucleophilic thiol groups can become oxidatively modified in response to diverse redox challenges...

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Detalles Bibliográficos
Autores principales: van Leeuwen, Lucie A.G., Hinchy, Elizabeth C., Murphy, Michael P., Robb, Ellen L., Cochemé, Helena M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488967/
https://www.ncbi.nlm.nih.gov/pubmed/28366801
http://dx.doi.org/10.1016/j.freeradbiomed.2017.03.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488967/
https://www.ncbi.nlm.nih.gov/pubmed/28366801
http://dx.doi.org/10.1016/j.freeradbiomed.2017.03.037

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