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Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function
Oxidative stress attributable to the activation of a Nox2-containing NADPH oxidase is involved in the development of vascular diseases and in aging. However, the mechanism of Nox2 activation in normal aging remains unclear. In this study, we used age-matched wild-type (WT) and Nox2 knockout (KO) mic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489050/ https://www.ncbi.nlm.nih.gov/pubmed/28499911 http://dx.doi.org/10.1016/j.freeradbiomed.2017.05.008 |