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Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function

Oxidative stress attributable to the activation of a Nox2-containing NADPH oxidase is involved in the development of vascular diseases and in aging. However, the mechanism of Nox2 activation in normal aging remains unclear. In this study, we used age-matched wild-type (WT) and Nox2 knockout (KO) mic...

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Detalles Bibliográficos
Autores principales:	Fan, Lampson M., Cahill-Smith, Sarah, Geng, Li, Du, Junjie, Brooks, Gavin, Li, Jian-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489050/ https://www.ncbi.nlm.nih.gov/pubmed/28499911 http://dx.doi.org/10.1016/j.freeradbiomed.2017.05.008

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