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Validating α-particle emission from (211)At-labeled antibodies in single cells for cancer radioimmunotherapy using CR-39 plastic nuclear track detectors

Recently, (211)At has received increasing attention as a potential radionuclide for cancer radioimmunotherapy. It is a α-particle emitter, which is extremely effective against malignant cells. We demonstrate a method to verify the efficiency of (211)At-labeled trastuzumab antibodies ((211)At-trastuz...

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Detalles Bibliográficos
Autores principales: Kodaira, Satoshi, Li, Huizi Keiko, Konishi, Teruaki, Kitamura, Hisashi, Kurano, Mieko, Hasegawa, Sumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489156/
https://www.ncbi.nlm.nih.gov/pubmed/28658304
http://dx.doi.org/10.1371/journal.pone.0178472