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Reversible perturbations of gene regulation after genome editing in Drosophila cells
The prokaryotic phage defense CRISPR/cas-system has developed into a versatile toolbox for genome engineering and genetic studies in many organisms. While many efforts were spent on analyzing the consequences of off-target effects, only few studies addressed side-effects that occur due to the target...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489201/ https://www.ncbi.nlm.nih.gov/pubmed/28658280 http://dx.doi.org/10.1371/journal.pone.0180135 |