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Next-generation sequencing of the human TRPV1 gene and the regulating co-players LTB4R and LTB4R2 based on a custom AmpliSeq(™) panel

BACKGROUND: Transient receptor potential cation channel subfamily V member 1 (TRPV1) are sensitive to heat, capsaicin, pungent chemicals and other noxious stimuli. They play important roles in the pain pathway where in concert with proinflammatory factors such as leukotrienes they mediate sensitizat...

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Detalles Bibliográficos
Autores principales: Kringel, Dario, Sisignano, Marco, Zinn, Sebastian, Lötsch, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489211/
https://www.ncbi.nlm.nih.gov/pubmed/28658281
http://dx.doi.org/10.1371/journal.pone.0180116