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HIV virions sense plasma membrane heterogeneity for cell entry

It has been proposed that cholesterol in host cell membranes plays a pivotal role for cell entry of HIV. However, it remains largely unknown why virions prefer cholesterol-rich heterogeneous membranes to uniformly fluid membranes for membrane fusion. Using giant plasma membrane vesicles containing c...

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Detalles Bibliográficos
Autores principales: Yang, Sung-Tae, Kreutzberger, Alex J. B., Kiessling, Volker, Ganser-Pornillos, Barbie K., White, Judith M., Tamm, Lukas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489272/
https://www.ncbi.nlm.nih.gov/pubmed/28782011
http://dx.doi.org/10.1126/sciadv.1700338