Cargando…

Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis

The surface topography of synthetic biomaterials is known to play a role in material-driven osteogenesis. Recent studies show that TGFβ signalling also initiates osteogenic differentiation. TGFβ signalling requires the recruitment of TGFβ receptors (TGFβR) to the primary cilia. In this study, we hyp...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jingwei, Dalbay, Melis T., Luo, Xiaoman, Vrij, Erik, Barbieri, Davide, Moroni, Lorenzo, de Bruijn, Joost D., van Blitterswijk, Clemens A., Chapple, J. Paul, Knight, Martin M., Yuan, Huipin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489417/
https://www.ncbi.nlm.nih.gov/pubmed/28456657
http://dx.doi.org/10.1016/j.actbio.2017.04.004