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Dual role of cellular prion protein in normal host and Alzheimer’s disease
Using PrP(C)-knockout cell lines, it has been shown that the inhibition of apoptosis through STI1 is mediated by PrP(C)-dependent SOD activation. Antioxidant PrP(C) may contribute to suppression of inflammasome activation. PrP(C) is functionally involved in copper metabolism, signal transduction, ne...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japan Academy
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489426/ https://www.ncbi.nlm.nih.gov/pubmed/28413194 http://dx.doi.org/10.2183/pjab.93.010 |