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Purinergic signaling in microglia in the pathogenesis of neuropathic pain
Nerve injury often causes debilitating chronic pain, referred to as neuropathic pain, which is refractory to currently available analgesics including morphine. Many reports indicate that activated spinal microglia evoke neuropathic pain. The P2X4 receptor (P2X4R), a subtype of ionotropic ATP recepto...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japan Academy
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489427/ https://www.ncbi.nlm.nih.gov/pubmed/28413195 http://dx.doi.org/10.2183/pjab.93.011 |