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Chemical and structural biology of protein lysine deacetylases

Histone acetylation is a reversible posttranslational modification that plays a fundamental role in regulating eukaryotic gene expression and chromatin structure/function. Key enzymes for removing acetyl groups from histones are metal (zinc)-dependent and NAD(+)-dependent histone deacetylases (HDACs...

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Detalles Bibliográficos
Autores principales: YOSHIDA, Minoru, KUDO, Norio, KOSONO, Saori, ITO, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489435/
https://www.ncbi.nlm.nih.gov/pubmed/28496053
http://dx.doi.org/10.2183/pjab.93.019