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Chemical and structural biology of protein lysine deacetylases
Histone acetylation is a reversible posttranslational modification that plays a fundamental role in regulating eukaryotic gene expression and chromatin structure/function. Key enzymes for removing acetyl groups from histones are metal (zinc)-dependent and NAD(+)-dependent histone deacetylases (HDACs...
Autores principales: | YOSHIDA, Minoru, KUDO, Norio, KOSONO, Saori, ITO, Akihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Academy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489435/ https://www.ncbi.nlm.nih.gov/pubmed/28496053 http://dx.doi.org/10.2183/pjab.93.019 |
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