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Days weaving the lagging strand synthesis of DNA — A personal recollection of the discovery of Okazaki fragments and studies on discontinuous replication mechanism —
At DNA replication forks, the overall growth of the antiparallel two daughter DNA chains appears to occur 5′-to-3′ direction in the leading-strand and 3′-to-5′ direction in the lagging-strand using enzyme system only able to elongate 5′-to-3′ direction, and I describe in this review how we have anal...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japan Academy
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489436/ https://www.ncbi.nlm.nih.gov/pubmed/28496054 http://dx.doi.org/10.2183/pjab.93.020 |