Mmm-derived lipid-associated membrane proteins activate IL-1β production through the NF-κB pathway via TLR2, MyD88, and IRAK4

Mycoplasma mycoides subsp.mycoides (Mmm) is a pathogen that causes pneumonia, otitis media, and arthritis in young calves. Its pathogenesis is attributed in part to excessive immune responses. Mmm-derived lipid-associated membrane proteins (LAMPs) are potent inducers of the host innate immune system...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Wang, Qi, Li, Yuan, Chen, Ying, Shao, Jiari, Nick, Nwankpa, Li, Chunyan, Xin, Jiuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489475/
https://www.ncbi.nlm.nih.gov/pubmed/28659605
http://dx.doi.org/10.1038/s41598-017-04729-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489475/
https://www.ncbi.nlm.nih.gov/pubmed/28659605
http://dx.doi.org/10.1038/s41598-017-04729-y

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