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Palmitic Acid-BSA enhances Amyloid-β production through GPR40-mediated dual pathways in neuronal cells: Involvement of the Akt/mTOR/HIF-1α and Akt/NF-κB pathways

The pathophysiological actions of fatty acids (FAs) on Alzheimer’s disease (AD), which are possibly mediated by genomic effects, are widely known; however, their non-genomic actions remain elusive. The aim of this study was to investigate the non-genomic mechanism of extra-cellular palmitic acid (PA...

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Detalles Bibliográficos
Autores principales: Kim, Jeong Yeon, Lee, Hyun Jik, Lee, Sei-Jung, Jung, Young Hyun, Yoo, Dae Young, Hwang, In Koo, Seong, Je Kyung, Ryu, Jung Min, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489526/
https://www.ncbi.nlm.nih.gov/pubmed/28659580
http://dx.doi.org/10.1038/s41598-017-04175-w