Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2

Matrix metalloproteinases (MMPs) are regulated at multiple transcriptional and post-transcriptional levels, among which receptor-mediated endocytic clearance. We previously showed that low-density lipoprotein receptor-related protein-1 (LRP-1) mediates the clearance of a complex between the zymogen...

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Detalles Bibliográficos
Autores principales: Johanns, Manuel, Lemoine, Pascale, Janssens, Virginie, Grieco, Giuseppina, Moestrup, Soren K., Nielsen, Rikke, Christensen, Erik I., Courtoy, Pierre J., Emonard, Hervé, Marbaix, Etienne, Henriet, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489529/
https://www.ncbi.nlm.nih.gov/pubmed/28659595
http://dx.doi.org/10.1038/s41598-017-04648-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489529/
https://www.ncbi.nlm.nih.gov/pubmed/28659595
http://dx.doi.org/10.1038/s41598-017-04648-y

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