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Pekinenin E Inhibits the Growth of Hepatocellular Carcinoma by Promoting Endoplasmic Reticulum Stress Mediated Cell Death

Hepatocellular carcinoma (HCC) is a malignant primary liver cancer with poor prognosis. In the present study, we report that pekinenin E (PE), a casbane diterpenoid derived from the roots of Euphorbia pekinensis, has a strong antitumor activity against human HCC cells both in vitro and in vivo. PE s...

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Detalles Bibliográficos
Autores principales: Fan, Lu, Xiao, Qingling, Chen, Yanyan, Chen, Gang, Duan, Jinao, Tao, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489557/
https://www.ncbi.nlm.nih.gov/pubmed/28706487
http://dx.doi.org/10.3389/fphar.2017.00424